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Lung Tumor Modeling

Investigators

Juergen Meyer, Ph.D.

Summary

The aim of this research is to develop a semi-realistic 3D model, which aims to physically model the spatial relationship between an external signal, representing abdominal breathing motion, and a lung tumor. The approach is based on an array of springs and dashpots arranged to model tumours at any location within the lung. While the mathematical model is general for any tumor in the lung, the parameters governing the springs and dashpots are patient- and tumour location specific.

Citations

E J Ackerley, A E Cavan, P L Wilson, R I Berbeco, J Meyer, Application of a spring-dashpot system to clinical lung tumor motion data, Medical Physics (accepted for publicaion)

P L Wilson, J Meyer, A General Model of Lung Tumour Motion, Mathematics and Industry, 15(3), 1061-6, 2010

P L Wilson, J Meyer, A spring-dashpot system for modelling lung tumour motion in radiotherapy, Computational and Mathematical Methods in Medicine, 11(1), 2010 (pdf)

A Cavan, P L Wilson, R Berbeco, J Meyer, A viscoelastic model of the correlation between respiratory lung tumour motion and an external abdominal signal, presented at Engineering and Physical Sciences in Medicine (EPSM 2010), Melbourne, Australia, 05-09 December 2010

A Cavan, P Wilson and J Meyer, A viscoelastic model of respiratory lung tumour motion, The New Zealand Medical Journal, Proceedings of the Health Research Society of Canterbury Seminar Series 123 (1313), 85 (2010)

P L Wilson , J Meyer. A general model of lung tumour motion”, Poster presented at the European Consortium for Mathematics in Industry (ECMI 2008), University College London, London, UK. 30th June – 4th July 2008

J. Meyer and P. Wilson, A three dimensional spring-dashpot system to model the correlation between abdominal and lung tumour motion, presented at the Engineering and Physical Sciences in Medicine and the Australian Biomedical Engineering Conference (EPSM ABEC 2008), Christchurch, New Zealand, 2008, pp. 389.

J Meyer, K Lenz, P L Wilson, J Wilbert, M Guckenberger, A Richter and K Baier. Modelling tumour trajectories as a function of respiratory motion. Presented at: Engineering and Physical Sciences in Medicine and The Australian Biomedical Engineering Conference (EPSM-ABEC), Perth, WA, Australia. October 14-18, 2007. p. 100