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Wade Smith, PhD, DABR

Associate Professor

Education and Training

College: Lawrence University, Appleton WI

Graduate School: SUNY Stony Brook, Stony Brook, NY


  • Postdoctoral Fellow, Clinical Research Division, Geraghty Lab, Fred Hutchinson Cancer Research Center and Department of Genome Sciences, University of Washington, Seattle WA
  • Senior Fellow, Department of Radiation Oncology, University of Washington, Seattle WA

Selected Publications

Smith, W.P., Young, L.A., Phillips, M.H., Cheung, M., Halasz, L.M., Rockhill, J.K, (2017) “Clinical Positioning Accuracy Including Edentulous Patients for Multisession Stereotactic Radiotherapy with the Gamma Knife Perfexion,” Technology in Cancer Research & Treatment, 2017 May 17, 10.1177/1533034617708884

Gopan, O., A. Kalet, W.P. Smith, K. Hendrickson, M. Kim, L. Young, M. Nyflot, A. Chvetsov, M. Phillips, and E. Ford. “WE-H-BRC-09: Simulated Errors in Mock Radiotherapy Plans to Quantify the Effectiveness of the Physics Plan Review.” Medical Physics 43, no. 6 (2016): 3841-3842.

Richard, P., Phillips, M.H., Smith, W.P., Davidson, D., Kim, E.Y., Kane, G.M. (2016). “Cost-Effectiveness Analysis of Intensity Modulated Radiation Therapy versus 3-Dimensional Conformal Radiation Therapy for Preoperative Treatment of Extremity Soft Tissue Sarcomas.” International Journal of Radiation Oncology Biology Physics, 2016 Feb 6. pii:S0360-3016(16)00119-X.

Smith, W.P., Kim M., Holdsworth C., Liao J., Phillips M.H. (2016) “Personalized treatment planning with a model of radiation therapy outcomes for use in multiobjective optimization of IMRT plans for prostate cancer.” Radiation Oncology 2016;11(1):38.

Meyer, J., Nyflot, M.J., Smith, W.P., Wottoon, L.S., Young, L., Yang, F., Kim, M., Hendrickson, K., Ford, E., Kaley, A.M., Cao, N. (2016). “Electron beam energy QA – a note on measurement tolerances.” Journal of Applied Clinical Medical Physics, 17(2).

Smith, W.P., Phillips, M.H. (2015) Comment on “ROC analysis in patient specific quality assurance” [Med. Phys. 40(4), 042103.)], Medical Physics 42(7):4411-2.

Phillips, M.H., Meyer, J., Smith, W.P., & Rockhill, J.K. (2014). Organism level models: When mechanisms and statistics fail us. Journal of Physics: Conference Series (Vol. 489, No. 1, p. 012096). IOP Publishing.

Phillips, M.H., Smith, W.P., Parvathaneni, U., & Laramore, G.E. (2011). Role of positron emission tomography in the treatment of occult disease in head-and-neck cancer: a modeling approach. International Journal of Radiation Oncology Biology Physics, 79(4), 1089-1095.

Hendrickson, K., Phillips, M., Smith, W.P., Peterson, L., Krohn, K., & Rajendran, J. (2011). Hypoxia imaging with [F-18] FMISO-PET in head and neck cancer: potential for guiding intensity modulated radiation therapy in overcoming hypoxia-induced treatment resistance. Radiotherapy and Oncology, 101(3), 369-375.

Smith, W.P., Doctor, J., Meyer, J., Kalet, I.J., & Phillips, M.H. (2009). A decision aid for intensity-modulated radiation-therapy plan selection in prostate cancer based on a prognostic Bayesian network and a Markov model. Artificial intelligence in medicine, 46(2), 119-130.

Research Interests

  • Decision Theory in Radiation Oncology
  • The role of uncertainty in clinical decision making and clinical trials
  • QALY calculations and cost-benefit analysis
  • Surface imaging
  • Gamma Knife Radiosurgery, and stereotactic radiotherapy
  • Adaptive RT

Clinical Interests

  • Surface Imaging
  • Adaptive RT
  • Gamma Knife Radiosurgery

Educational Involvement

  • Mentor of QA rotation

Professional Involvement

  • Member of AAPM, ASTRO, and Society of Medical Decision Making (SMDM)
  • Member of AAPM Work Group on Clinical Trials
  • Member of AAPM Machine Learning Sub Committee
  • Member of ASTRO Comparative Effectiveness Research (CER) Resource Panel