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Smith “Jim” Apisarnthanarax, M.D.

Associate Professor


Dr. Apisarnthanarax is a radiation oncologist with expertise in gastrointestinal cancers and genitourinary tumors, including prostate cancer. He also specializes in proton therapy, stereotactic body radiation therapy, and liver cancer.

Patient Care Philosophy

“Being diagnosed with and treated for cancer is one of the most arduous journeys that any person will experience. Every patient and every cancer is different. As a radiation oncologist, my goal is to guide patients through this difficult time by providing the most compassionate, personalized care possible and making sure they have access to the latest, innovative clinical trials and state-of-art technology.”

Education and Training

College: Brown University, Providence, RI, 1998

Medical Education: Brown University Warren Alpert Medical School, Providence, RI, 2002

Internship: Northwestern University – Evanston Hospital, Evanston, IL, 2003

Fellowship: Experimental Radiation Oncology, M.D. Anderson Cancer Center, Houston, TX, 2005

Residency: Radiation Oncology, University of North Carolina, Chapel Hill, NC, 2009

Selected Publications from a Total of 32

Sharma S, Whaley JT, Zou W, Shepherd AF, Xanthopoulos EP, Christodouleas, Both S, Rengan R, Simone II CB, Apisarnthanarax S. Incidental nodal irradiation in locally advanced non-small cell lung cancer treated with involved-field IMRT. Applied Radiation Oncology, accepted.

Matesan MM, Bowen SR, Chapman TR, Miyaoka RS, Velez JW, Wanner MF, Nyflot MJ, Apisarnthanarax S, Vesselle HJ. Assessment of functional liver reserve: old and new in [99mTc]sulfur colloid scintigraphy. Nuclear Medicine Communication, June 2017, 10.1097/MNM.0000000000000695. PMID 28591006.

Boimel PJ, Berman AT, Li J, Apisarnthanarax S, Both S, Lelionis K, Larson GL, Teitelbaum U, Lukens JN, Ben-Josef E, Metz JM, Plastaras JP. Proton beam reirradiation for locally recurrent pancreatic adenocarcinoma. Journal of Gastrointestinal Oncology, accepted.

Mullen TD, Kim EY, Apisarnthanarax S. Short-course radiation therapy versus long-course chemoradiation in the neoadjuvant treatment of locally advanced rectal cancer: new insights from randomized trials. Current Colorectal Cancer Reports, in press.

Tseng YD, Apisarnthanarax S, Liao JL, Bhatia S, Nghiem PT, Parvathaneni U. Factors influencing radiation treatment recommendations in early-stage Merkel cell carcinoma: a survey of US-based radiation oncologists. Expert Review of Anticancer Therapy Jan 2017, 10.1080/14737140.2017.1285233. PMID: 28103445.

Zeng YC, Vyas S, Dang Q, Shultz L, Bowen SR, Shankaran V, Farjah F, Oelschlager BK, Apisarnthanarax S, Zeng J. Proton therapy posterior beam approach with pencil beam scanning for esophageal cancer: clinical outcome, dosimetry, and feasibility. Strahlentherapie Onkologie 192(12): 913-921, Dec 2016. PMID: 27596221.

Bowen SR, Chapman TR, Borgman J, Miyaoka RS, Kinahan PE, Liou IW, Sandison GA, Vesselle HJ, Nyflot MJ, Apisarnthanarax S. Measuring total liver function on sulfur colloid SPECT/CT for improved risk stratification and outcome prediction of hepatocellular carcinoma patients. European Journal of Nuclear Medicine and Molecular Imaging Research 6(1): 57, Dec 2016. PMID: 27349530.

Coveler AL, Richard P, Apisarnthanarax S, Chiorean EG. Is there a best radiosensitizing agent in the treatment of locally advanced rectal cancer? Current Colorectal Cancer Reports 12(4): 189-200, Aug 2016.

Apisarnthanarax S, Chia-Hsien Cheng J, Jabbour SK, Liauw SL, Murphy JD, Chang DT.   Gastrointestinal cancers-changing the standard for rectal cancer and establishing a new standard for liver tumors. International Journal of Radiation Oncology, Biology, Physics 95(3): 930-6, Jul 2016. PMID: 27302509.

Yeh MM, Yeung RS, Apisarnthanarax S, Bhattacharya R, Cuevas C, Harris WP, Hon TLK, Padia SA, Park JO, Riggle KM, Daoud SS. Multidisciplinary perspective of hepatocellular carcinoma: a pacific northwest experience. World Journal of Hepatology 7(11): 1460-1483, June 2015. PMID: 26085907.

To see more of Dr. Apisarnthanarax’s publications, please click here.

Research Interests

  • Functional Imaging for Liver Cancer
  • GI Proton Treatment
  • Radiation Oncology and Diagnostic Radiology Imaging