Get in touch today 206.598.4100 or

Schedule an Appointment

R. Alex Hsi, MD

Clinical Assistant Professor

Locations of Practice


Dr. R. Alex Hsi is a board-certified Radiation Oncologist who received his medical degree from the University of Michigan in 1991.  He completed a residency in Internal Medicine at the University of Michigan followed by a residency in Radiation Oncology at The University of Pennsylvania.  He has served as an Assistant Professor in Radiation Oncology at the University of Pennsylvania, Section Chief in the Department of Radiation Oncology at Virginia Mason Medical Center in Seattle, Washington, and Medical Director of the Prostate Cancer Center of Seattle.  He is also Co-founder of the Peninsula Cancer Center in Poulsbo, Washington.  He serves as the President of the Board of the Prostate Cancer Free Foundation.

Dr. Hsi has performed over a thousand prostate seed brachytherapy procedures since 1997.  In addition to prostate brachytherapy, Dr. Hsi’s areas of interest include stereotactic radiation therapy for prostate and lung cancer and photodynamic therapy.  Dr. Hsi is the recipient of several peer-reviewed grants and has served as principal investigator of multiple clinical trials involving prostate cancer research.

Patient Care Philosophy

Radiation Oncology is a challenging and rewarding field. In the modern era of scientific, technology-oriented medicine, it’s vital that we, as physicians, also remember to practice the art of medicine by perfecting our listening skills and working to understand all of our patient’s needs.

Education and Training

College: Kalamazoo College, Kalamazoo, MI (1987)

Medical Education: University of Michigan Medical School, Ann Arbor, MI (1991)

Selected Publications from a Total of 25

Quinn TJ, Daignault-Newton S, Bosch W, Mariados N, Sylvester J, Shah D, Gross E, Hudes R, Beyer D, Kurtzman S, Bogart J, Hsi RA, et al.  Who Benefits From a Prostate Rectal Spacer? Secondary Analysis of a Phase III Trial.  Practical Radiation Oncology, 10:186-194, 2020.

Hamstra D, Mariados N, Sylvester J, Shah D, Karsh L, Hudes R, Beyer D, Kurtzman S, Bogart J, Hsi RA, et al.  Continued Benefit to Rectal Separation for Prostate Radiation Therapy:  Final Results of a Phase III Trial.  Int J Radiation Oncology Biol Phys, 97(5): 976-985, 2017.

Madsen BL, Hsi RA, Pham HT, Fowler JF, Esagui L, Corman J.  Stereotactic hypofractionated accurate radiotherapy of the prostate (SHARP), 33.5 Gy in five fractions for localized disease:  first clinical trial results.  Int J Radiation Oncology Biol Phys, 67:1099-1105, 2007.

Hsi RA, Kapatkin A, Strandberg J, Zhu T, Vulcan T, Solonenko M, Rodriguez C, Chang J, Saunders M, Mason N, Hahn SM.  Photodynamic therapy in the canine prostate using Motexafin Lutetium.  Clinical Cancer Research, 7:651-660, 2001.

Hsi RA.  Focal Brachytherapy and Intensity-Modulated Radiation Therapy.  In:  Imaging and Focal Therapy of Early Prostate Cancer.  Polascik TJ (ed).  Switzerland:  Springer, 2017.

Research Interests

Focal salvage brachytherapy for prostate cancer

Outcomes of MR fusion transperineal prostate biopsies

Stereotactic body radiation therapy for prostate and lung cancer

Comparative effectiveness of prostate cancer treatments