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Boryana Eastman, MD

Education and Training

College: Wellesley College, Wellesley, MA; Biological Chemistry

Graduate School: University of California San Diego, La Jolla, CA; Biomedical Sciences

Medical Education: University of California, San Diego, CA

Published works

Eastman, B.M., Jo, M., Webb, D.L., Takimoto, S., Gonias, S.L.. A transformation in the mechanism by which the urokinase receptor signals provides a selection advantage for estrogen receptor-expressing breast cancer cells in the absence of estrogen. Cell Signaling. 2012, Sep; 24(9): 1847-55.

Hu, J., Jo, M., Eastman, B.M., Gilder, A.S., Bui, J.D., Gonias, S.L.. uPAR induces expression of transforming growth factor beta and interleukin-4 in cancer cells to promote tumor permissive conditioning of macrophages.. American Journal of Pathology. 2014, Dec; 184(12): 3384-93.

Jo, M., Eastman, B.M., Webb, D.L., Stoletov, K., Klemke, R., Gonias, S.L.. Cell signaling by urokinase-type plasminogen activator receptor induces stem cell like properties in breast cancer cells M. Jo and B.M. Eastman contributed equally to this work. Cancer Research. 2010, Nov; 70(21): 8948-58.

Jo, M., Lester, R.D., Montel, V., Eastman, B., Takimoto, S., Gonias, S.L.. Reversibility of epithelial-mesenchymal transition (EMT) induced in breast cancer cells by activation of urokinase receptor-dependent cell signalling. J Biol Chem. 2009, Aug; 284(34): 22825-33.